Corneal Cross-Linking

What is Cross-Linking?

Corneal collagen cross-linking is a medical procedure that combines the use of ultraviolet (UV) light and riboflavin (vitamin B2) eye drops. The cross-linking procedure creates new corneal collagen cross-links and results in a shortening and thickening of the collagen fibrils. This leads to an overall stiffening of the cornea. It is important to be evaluated for this procedure before the corneal steepening has advanced too far. Once the steepening has reached a certain point, a cornea transplant may be necessary to restore good vision.

Corneal cross-linking is the only FDA-approved therapeutic treatment for progressive keratoconus and corneal ectasia (steepening) following refractive surgery. Avedro’s KXL System is the only FDA approved cross-linking device in the United States.

Corneal cross-linking is a procedure that should be performed by an ophthalmologist that is trained in advanced corneal procedures and post-operative corneal healing. Your doctor is a cornea specialist who has had extensive experience with keratoconus patients. We hope that this innovative procedure may reduce the amount of corneal transplantations needed in this patient group.